Kenneth E White Selected Research

Autosomal Dominant Hypophosphatemic Rickets

7/2014	Coupling fibroblast growth factor 23 production and cleavage: iron deficiency, rickets, and kidney disease.
2/2014	Neonatal iron deficiency causes abnormal phosphate metabolism by elevating FGF23 in normal and ADHR mice.
6/2013	Osteocyte regulation of phosphate homeostasis and bone mineralization underlies the pathophysiology of the heritable disorders of rickets and osteomalacia.
11/2011	Iron deficiency drives an autosomal dominant hypophosphatemic rickets (ADHR) phenotype in fibroblast growth factor-23 (Fgf23) knock-in mice.
8/2005	Fibroblast growth factor 23 and its receptors.
4/2005	A novel recessive mutation in fibroblast growth factor-23 causes familial tumoral calcinosis.
4/2005	FGF23 and disorders of phosphate homeostasis.
8/2004	FGF23 is processed by proprotein convertases but not by PHEX.
4/2003	Fibroblast growth factor 23 in oncogenic osteomalacia and X-linked hypophosphatemia.

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Kenneth E White Research Topics

Disease

12	Hyperphosphatemia 01/2021 - 04/2005
11	Hypophosphatemia 04/2016 - 04/2003
10	Chronic Renal Insufficiency 01/2022 - 01/2009
9	Autosomal Dominant Hypophosphatemic Rickets 07/2014 - 04/2003
8	Osteomalacia 04/2016 - 01/2004
8	Rickets (Rachitis) 04/2016 - 01/2004
7	Calcinosis 10/2016 - 04/2005
7	Oncogenic osteomalacia 09/2009 - 04/2003
6	Familial Hypophosphatemic Rickets (X-Linked Hypophosphatemia) 04/2016 - 04/2003
6	Neoplasms (Cancer) 06/2014 - 04/2003
5	Hypoxia (Hypoxemia) 01/2022 - 02/2014
5	Vascular Calcification 04/2017 - 04/2005
5	Hypophosphatemic Rickets 09/2014 - 11/2006
4	Anemia 01/2022 - 02/2014
4	Iron Deficiencies 01/2022 - 11/2011
3	Iron-Deficiency Anemia (Anemia, Iron Deficiency) 01/2022 - 06/2017
3	Familial Hypophosphatemia (Phosphate Diabetes) 01/2020 - 04/2003
3	Chronic Kidney Disease-Mineral and Bone Disorder (Renal Rickets) 07/2017 - 01/2009
2	Familial Hyperphosphatemic Tumoral Calcinosis 10/2014 - 06/2014
2	Kidney Diseases (Kidney Disease) 07/2014 - 01/2009
2	Pain (Aches) 06/2014 - 08/2005
2	Hypercalcemia (Milk Alkali Syndrome) 01/2009 - 09/2007
2	Fibrous Dysplasia of Bone 04/2005 - 09/2003
2	Osteopetrosis 08/2003 - 05/2002
1	Fibrosis (Cirrhosis) 01/2020
1	Diabetic Nephropathies (Diabetic Nephropathy) 01/2019
1	Endocrine System Diseases (Endocrine Diseases) 01/2019
1	Cardiomegaly (Heart Hypertrophy) 01/2019
1	Rare Diseases (Rare Disease) 07/2017
1	Calcinosis Cutis 10/2016
1	Heterotopic Ossification (Ectopic Ossification) 10/2016
1	Inflammation (Inflammations) 10/2016
1	Camurati-Engelmann Syndrome (Progressive Diaphyseal Dysplasia) 10/2016
1	Hyperostosis-hyperphosphatemia syndrome 10/2016
1	Infertility (Sterility) 01/2016
1	Bone Diseases (Bone Disease) 01/2016
1	Cardiovascular Diseases (Cardiovascular Disease) 07/2014
1	Acidosis 06/2014
1	Raine syndrome 04/2014
1	Developmental Bone Diseases (Bone Dysplasia) 04/2014
1	Hyperparathyroidism 06/2005
1	Renal Insufficiency (Renal Failure) 04/2005
1	Muscle Weakness 03/2005

Drug/Important Bio-Agent (IBA)

31	Phosphates (Orthophosphate)IBA 01/2022 - 04/2003
22	Fibroblast Growth Factor-23IBA 01/2022 - 04/2003
10	MineralsIBA 01/2021 - 11/2006
7	Hormones (Hormone)IBA 01/2021 - 04/2014
7	Vitamin D FDA LinkGeneric 01/2020 - 06/2005
7	Proteins (Proteins, Gene)FDA Link 06/2014 - 01/2004
5	IronIBA 01/2022 - 11/2011
5	Phosphorus (Red Phosphorus)IBA 01/2021 - 03/2005
4	Messenger RNA (mRNA)IBA 01/2020 - 04/2003
4	1,25-dihydroxyvitamin DIBA 09/2005 - 03/2005
3	Prolyl-Hydroxylase InhibitorsIBA 01/2022 - 01/2020
3	Erythropoietin FDA Link 01/2022 - 01/2020
3	Calcitriol (Calcijex)FDA LinkGeneric 10/2016 - 04/2005
3	EndopeptidasesIBA 04/2016 - 04/2003
3	Parathyroid Hormone (Parathormone)IBA 01/2009 - 03/2005
2	ferric citrateIBA 01/2022 - 01/2022
2	NitrogenIBA 01/2021 - 01/2019
2	Urea (Carbamide)FDA LinkGeneric 01/2021 - 01/2019
2	Phosphate Transport Proteins (Phosphate Transporter)IBA 01/2020 - 04/2010
2	hydroxide ionIBA 01/2009 - 10/2007
2	GalactosamineIBA 09/2007 - 10/2006
2	Uridine Diphosphate (UDP)IBA 09/2007 - 10/2006
2	Polypeptide N-acetylgalactosaminyltransferaseIBA 09/2007 - 10/2006
1	Pharmaceutical PreparationsIBA 01/2022
1	Chelating AgentsIBA 01/2021
1	molidustatIBA 01/2021
1	Transferrin (beta 2 Transferrin)IBA 01/2021
1	Vitamin D3 24-HydroxylaseIBA 01/2020
1	roxadustatIBA 01/2020
1	EnzymesIBA 01/2020
1	HematinicsIBA 01/2020
1	25-Hydroxyvitamin D3 1-alpha-Hydroxylase (25 Hydroxyvitamin D3 1 alpha Hydroxylase)IBA 01/2020
1	Fibroblast Growth Factor Receptors (Fibroblast Growth Factor Receptor)IBA 01/2020
1	Adenine FDA LinkGeneric 01/2019
1	Biological ProductsIBA 07/2017
1	LigandsIBA 07/2017
1	Transcription Factors (Transcription Factor)IBA 06/2017
1	RacivirIBA 10/2016
1	C-Reactive ProteinIBA 10/2016
1	Interleukin-1 (Interleukin 1)IBA 10/2016
1	Sevelamer (RenaGel)FDA Link 06/2014
1	Bicarbonates (Hydrogen Carbonate)IBA 06/2014
1	Acetazolamide (Diamox)FDA LinkGeneric 06/2014
1	Phosphotransferases (Kinase)IBA 04/2014
1	Oxygen (Dioxygen)IBA 02/2014
1	CateninsIBA 06/2013
1	SubtilisinIBA 06/2013
1	NucleotidesIBA 02/2009
1	CalciumIBA 01/2009
1	Dietary ProteinsIBA 01/2009
1	Caseins (Casein)FDA Link 01/2009
1	Parathyroid Hormone-Related ProteinIBA 01/2009
1	Initiator Codon (Start Codon)IBA 11/2006
1	Calcitriol Receptors (Calcitriol Receptor)IBA 06/2005
1	Alkaline PhosphataseIBA 03/2005

Therapy/Procedure

8	Therapeutics 01/2022 - 01/2004
1	Injections 10/2010